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Interviews from 2003

Question 8
When looking for genetic variation, does it make a difference to look at "coding" parts of the genome as opposed to "non-coding"?

Does it make a difference to look at "coding" parts of the genome as opposed to "non-coding"?

Answers:
Jonathan Marks

Molecular Anthropologist

If you look at pretty much any part of the genome that we know of, you would get about the same pattern. If you looked at any gene, at random, you'd probably get a pattern similar to what you found for the mitochondrial DNA. Because we know what the pattern is. Eighty-five percent of the detectable genetic variation, no matter what you look at, is within groups rather than between groups. Therefore, you're far more likely to find matches among people from different populations than you a...

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